Felipe Lombó

Felipe Lombó is Associate Professor of Microbiology at the Universidad de Oviedo, in Spain. He leads the research group “Biotechnology and Experimental Therapy based on Nutraceuticals (BITTEN)”, which is part of the Program in Translational Research at the Cancer Research Institute of this University, IUOPA. One research line is prevention of infections by bacterial pathogens (Bacillus cereus, Campylobacter jejuni, Cronobacter sakazakii, Clostridium perfringens, Escherichia coli, Listeria monocytogenes, Staphylococcus aureus, Salmonella spp., Shigella spp., etc.), by developing fast detection methods (DNA-based methods, optical biosensors, etc.) for them in drinking water, food, etc. Another research line is focused on prevention of diverse cancers (colon, breast, prostate) by using nutraceutical compounds (in vitro cellular models, animal models). Industrial production of these bioactive compounds is also achieved in bacterial factories (Streptomyces).  In the NOMORFILM project, this group carries out research on identification and isolation of new antimicrobial compounds from microalgae, effective against most common biofilm-forming bacteria and fungi, and also in increasing their production levels.

Relevant publications

Marín L, Miguélez EM, Villar CJ, Lombó F. Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties. Biomed Res Int. 2015;2015:905215.

Al-Mestarihi AH, Villamizar G, Fernández J, Zolova OE, Lombó F, Garneau-Tsodikova S. Adenylation and S-methylation of cysteine by the bifunctional enzyme TioN in thiocoraline biosynthesis. J Am Chem Soc. 2014 Dec 10;136(49):17350-4.

Fernández J, Marín L, Alvarez-Alonso R, Redondo S, Carvajal J, Villamizar G, Villar CJ, Lombó F. Biosynthetic modularity rules in the bisintercalator family of antitumor compounds. Mar Drugs. 2014 May 9;12(5):2668-99.

---